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Science % Research

The First Clinical Study Shows a Key NAD+ Intermediate NMN Safe for Human Use

A research team at Keio University has shown for the first time that nicotinamide mononucleotide (NMN), a promising compound for anti-aging intervention, can be safely administered to healthy humans. The...
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Impairment of an Endothelial NAD +-H 2 S Signaling Network Is a Reversible Cause of Vascular Aging

A decline in capillary density and blood flow with age is a major cause of mortality and morbidity. Understanding why this occurs is key to future gains in human health....
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Nicotinamide mononucleotide alters mitochondrial dynamics by SIRT3‐dependent mechanism in male mice

Nicotinamide adenine dinucleotide (NAD+) is a central signaling molecule and enzyme cofactor that is involved in a variety of fundamental biological processes. NAD+ levels decline with age, neurodegenerative conditions, acute brain...
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